Umuthi "Roncoleukin" ungowesigaba sama-immunostimulants futhi utholakala ngendlela yesisombululo somjovo esisebenziseka kalula. Ithuluzi linconywa ukuthi lisetshenziswe ekwelapheni izinja ekwelapheni izifo eziningi zezindlela ezahlukahlukene zokuqina futhi njengomuthi wokuvikela. Lesi sidakamizwa senziwe ngesisekelo se-interleukin-2 ejwayelekile yomuntu futhi sinezinhlobo eziningi zezinhlelo zokusebenza zesimanje sezilwane.
Ukunikeza umuthi
Lolu hlobo lwe-immunostimulant olusebenza kahle luhlukanisiwe namaseli emvubelo, ngakho-ke izindleko zalo zingabizi kakhulu kubanikazi abaningi bezinja. I-IL-2 ehlanganisiwe inomphumela omuhle kakhulu kuma-T-lymphocyte, lapho ukwanda kwawo kuqinisekisiwe ukuthi kuzokwanda.
Umphumela webhayoloji we-IL-2 uqukethe ithonya eliqondisiwe lesithako esisebenzayo ekukhuleni, ekuhlukaniseni nasekusebenziseni ama-monocyte, ama-lymphocyte, ama-macrophages, kanye namaseli e-oligodendroglial kanye nokwakheka kwamaselula kweLangerhans. Izinkomba zokusetshenziswa zinikezwa:
- i-immunodeficiency evamile eguquguqukayo;
- ukuhlangana komzimba okuhlangene;
- i-peritonitis enamandla;
- i-pancreatitis enamandla;
- i-osteomyelitis;
- i-endometritis;
- inyumoniya enamandla;
- ispsis;
- i-postpartum sepsis;
- isifo sofuba samaphaphu;
- ezinye izifo ezijwayelekile nezimbi kakhulu zasendaweni;
- ungenwe ukushisa okushisayo nokwamakhemikhali;
- izinhlobo ezisakazwayo nezasendaweni ezivamile zezinambuzane ezinobungozi neziyingozi;
- i-staphylococcus;
- eczema;
- i-bronchitis;
- utwayi;
- isifo kanye ne-enteritis;
- i-keratitis ne-rhinitis;
- i-chlamydia;
- ukusha noma isithwathwa;
- leptospirosis.
Ukunwetshwa kobubanzi bomphumela we-lyzing wamaseli we-effector kungenxa yokuqedwa kwezinhlobo ezincane zamagciwane, amaseli amabi futhi anegciwane, ahlinzeka ngokuvikela amasosha omzimba okuhloswe ngawo ukulwa namaseli wesimila, kanye nokubhujiswa kwamagciwane wezifo ezibangelwa amagciwane, amagciwane kanye nesikhunta.
Okuhlangenwe nakho kokusetshenziswa okusebenzayo kwesidakamizwa "iRoncoleukin" njenge-agent yokuvimbela ukuvimbela ukuthuthukiswa kwezifo zamehlo noma izimo zokucindezeleka kufundwe kahle. Kuyafaneleka futhi ukusebenzisa i- "Roncoleukin" lapho kunezinkinga zokuhlinzwa ngemuva kokuhlinzwa kanye nokugoma esilwaneni esinemilenze emine, uma kunesidingo, ukukhuthaza ukuzivikela esilwaneni esibuthakathaka noma esigugile.
Ngenxa yokwakheka kwayo okukhethekile, i- "Roncoleukin" iyakwazi ukulwa nemiphumela emibi yokulimala kanzima noma ukuqhekeka okuyinkimbinkimbi, kanye nokuqeda ukucindezeleka okude.
I-immunostimulant isebenza kahle ngazo zonke izinhlobo zemithi, kufaka phakathi imishanguzo ehlukahlukene elwa nokuvuvukala nonsteroidal kanye nemigomo. Okuhlukile kuvezwa ngamalungiselelo aqukethe i-corticosteroids ne-glucose.
Ukwakheka, ifomu lokukhishwa
Ukwakheka kwefomu lokulinganisa kufaka phakathi i-interleukin-2 ephindaphindekayo, kanye nezakhi eziningi ezisizayo ezimelwe yi-sodium lauryl sulfate, i-ammonium bicarbonate, i-mannitol, i-dithiothreitol namanzi. Isidakamizwa sitholakala ngesisombululo esicacile, esenzelwe imijovo engaphansi kwesikhumba nokujova.
Ukusetshenziswa kwemijovo engaphansi kwesikhumba kufaka ukufaka i-1.5-2.0 ml yesisombululo se-sodium chloride esingu-0.9% noma amanzi akhethekile okujova kulowo muthi. Ukuphathwa kwesixazululo ngomfutho kwenziwa nge-dropper, okuyindlela engcono kakhulu yezilwane ezibuthakathaka kakhulu noma ezigula kakhulu.
Kuyathakazelisa! Isidakamizwa singasetshenziselwa ukufakwa emakhaleni wesilwane noma ngenhloso yokuyifaka nge-catheter esinyeni nge-cystitis noma ezinye izifo zesistimu yomchamo.
Lapho ihanjiswa ngomlomo, okuqukethwe kwe-vial noma i-ampoule kuhlanjululwa ngo-10 ml we-sodium chloride, ngemuva kwalokho isixazululo siphuzwa kancane kancane futhi ngokucophelela esilwaneni. Ngaphansi kokujwayelekile, umuthi "Roncoleukin" unqunywa odokotela bezilwane ukuze basetshenziswe ngaphandle. Kulesi simo, amanxeba we-purulent afakwe isisombululo se-immunostimulating noma i-foci yokuvuvukala.
Imiyalo yokusetshenziswa
Emiyalweni yokusetshenziswa enamathiselwe kumuthi "Roncoleukin", kuneziyalezo eziningi maqondana nokusetshenziswa nokubalwa komthamo, okuxhomeke ngqo kusisindo sesilwane kanye nezimpawu zezifo.
Uma i-ejenti ibekiwe ngezinhloso zokwelapha, khona-ke kunconywa ukunamathela kumthamo olandelayo:
- Izifo ezibangelwa noma iyiphi i-microflora yebhaktheriya, amagciwane noma ukutheleleka kwefungal kudinga umjovo womuthi. Umthamo ungama-10,000-15,000 IU ngekhilogremu yesisindo sesilwane. Udokotela wezilwane uqoka imijovo emibili kuya kwemihlanu ngokuhambisana nesikhathi sokuphumula sansuku zonke;
- wezifo zomdlavuza, udokotela wezilwane ubeka imijovo emihlanu. Kulokhu, umthamo ukhethwa ngesilinganiso se-15,000-20,000 IU ngekhilogremu ngalinye lesisindo somzimba wesilwane. Izifundo ziyaphindwa njalo ngenyanga.
Ngezinhloso ze-prophylactic, kunconywa ukuthi kuhambisane nohlelo olulandelayo lokuchaza lomuthi "Roncoleukin":
- esigabeni sokugoma, umjovo ongena ngaphansi kwesikhumba unikezwa ngasikhathi sinye nokugoma noma usuku olulodwa ngaphambi kwawo. Isidakamizwa sikhishwa ngesilinganiso sama-5000 IU ngekhilogremu yesisindo sesilwane;
- ukukhuthazwa kokuzivikela komzimba ukuvimbela ukulimala kwezifo zefungal noma ezithathelwanayo kwenziwa ngomthamo wama-5000 IU ngekhilogremu yesisindo somzimba wesilwane;
- ukuvimbela ukuthuthukiswa kwezinkinga zangemva kokuhlinzwa, umjovo wesixazululo esenziwe ngomumo wenziwa ngaphambi noma ngokushesha ngemuva kokuhlinzwa, kanye nangemva kwezinsuku ezimbalwa ngomthamo ka-5000 IU / kg;
- ukuvimbela imithi yesimo sokucindezeleka ngesikhathi sokuhamba isikhathi eside, ngesikhathi sokubonisa umbukiso noma ukuvakashela emtholampilo wezilwane kubandakanya ukwethulwa komuthi ezinsukwini ezimbalwa ngaphambi kokuvezwa kwengcindezi;
- Ukubuyisa ukungatheleleki kwezilwane zasekhaya ezindala ezibuthakathaka, umthamo wesixazululo ubalwa ngokususelwa ekusetshenzisweni kwe-10,000 IU / kg. Imijovo emibili kuphela eyenziwe ngekhefu lezinsuku ezimbili.
Lapho kunqunywa umuthi wokuzivikela emzimbeni "Roncoleukin", kufanele kukhunjulwe ukuthi ukwelashwa okuphindiwe kwezifundo kwenziwa ngokuqinile njengoba kuyalelwe ngudokotela wezilwane ngemuva kwezinyanga ezintathu kuya kweziyisithupha.
Izimo
Umkhawulo omkhulu othinta ukuqokwa komuthi "Roncoleukin" ubukhona bokuzwela kakhulu enjeni entweni yayo esebenzayo - i-interleukin, kanye ne-allergen reaction kumvubelo noma ukutholakala kwanoma yiziphi izifo ezizimele emlandweni wesilwane.
Ngokucophelela okukhulu nangemithamo emincane, njalo ngaphansi kweso lodokotela wezilwane, i-immunostimulant "Roncoleukin" yesimanje inqunyelwe ekwelapheni izifo ezethulwe ngu:
- izilonda zokuqhuba uhlelo lwenhliziyo;
- izifo zokugeleza kwegazi kanye / noma uhlelo lwe-lymphatic;
- ukukhubazeka kwama-valve enhliziyo;
- ukungasebenzi kahle kwamaphaphu.
Inani elincane lokuphikisana kungenxa yendlela eyingqayizivele yokuthola isizukulwane esisha sama-immunostimulants, kanye nokuhlanzeka okuphezulu kwezinto zokusetshenziswa ezisetshenziselwe ukuthola umuthi "Roncoleukin".
Izinyathelo zokuzivikela
Zonke izingxenye zebhayoloji zomuthi ziyawohloka ngokushesha ngokwanele, ngakho-ke, umuthi wokuvikela umzimba kufanele ugcinwe esiqandisini ezingeni lokushisa elingu-2-9mayelanaC. Umuthi ohlanganisiwe unempilo eshalofini ephezulu yezinyanga ezingama-24 kuphela.
Okubalulekile! Yabelana ngokudla kwe-immunostimulant ngezidakamizwa eziqukethe i-glucose, futhi umphumela wokwelashwa we-Roncoleukin ungakhanselwa ngokuphelele ngama-corticosteroids.
I-ampoule ngemuva kokuvula kufanele isetshenziswe kungakapheli amahora angama-24. Ngaphakathi kwezimbiza ezivaliwe, i-immunostimulant igcina izakhiwo zayo cishe amasonto ambalwa. Ngaphambi kokusetshenziswa, kubalulekile ukunaka ukubonakala koketshezi, okufanele kube okusobala, ngaphandle kwezigaxa, amahlule kanye nokugobhoza.
Okuqhamuka uma udla imishanguzo
Ukwedlula umthamo obekwe ngudokotela wezilwane kuhambisana ne-tachycardia, umkhuhlane, ukwehla kwengcindezi yegazi, nokuqubuka kwesikhumba.
Imvamisa, isimo sesilwane sijwayeleka sodwa ngokushesha ngemuva kokuphela komuthi, futhi kufanele kumiswe ukusabela okweqile nokwanda kokushisa komzimba ngezidakamizwa eziyizimpawu, kufaka phakathi izidakamizwa ezahlukahlukene ezilwa nokuvuvukala ezingezona ezokuhlasela kanye nama-analeptics anamuhla.
Kuyathakazelisa! Endaweni yomjovo, ukumiswa nokubomvu kungabonakala kwesinye isikhathi, okuvame ukuzihambela ngokwabo ezinsukwini ezintathu futhi akudingi ukwelashwa.
Izindleko ze-immunostimulant "Roncoleukin" yezinja
Umuthi "Roncoleukin" ngesisombululo uhlanganiswe kuma-ampoules anezilinganiso ezahlukahlukene, ngakho-ke izindleko ze-ejenti yokuzivikela yokuvikela enjalo ziyahlukahluka:
- Intengo ye-ampoule ye-1 ml ye-50,000 IU ephaketheni No. 3 ingama-ruble angama-210;
- Intengo ye-ampoule ye-1 ml ye-100,000 IU ephaketheni No. 3 ingama-ruble angama-255;
- Intengo ye-ampoule engu-1 ml 250,000 IU ephaketheni No. 3 ingama-ruble angama-350;
- Intengo ye-ampoule ye-1 ml ye-500,000 IU ephaketheni No. 3 ingama-ruble angama-670;
- Intengo ye-1 ml ampoule ye-2,000,000 IU ephaketheni No. 3 ingama-ruble ayi-1600-1700.
Izindleko zangempela zomuthi ezikhemisi yezilwane zingahluka kakhulu ngokuya ngesifunda kanye nenqubomgomo yentengo yendawo yokuthengisa.
Kuyathakazelisa! "I-Roncoleukin" iyi-immunomodulator yesizukulwane esilandelayo elinganiselayo, eyabhajethi futhi esebenzayo, eyayitholwe njengomuthi wabantu ekuqaleni, ngakho-ke izindleko zayo azikwazi ukuba phansi kakhulu.
Izibuyekezo mayelana nomuthi "Roncoleukin"
Ngenxa yokwakheka nokwenziwa kwamasu ayingqayizivele, isizukulwane esisha somuthi wokuzivikela emzimbeni "Roncoleukin" awunazo izifaniso okwamanje. Ezimweni zemithi yesimanje yezilwane, kusetshenziswa namuhla izivikeli mzimba eziningi zamanani ahlukahlukene nokwakheka, izigaba zazo ezibandakanya i-Interferon, i-Altevir ne-Famvir, kepha kumkhiqizo weRoncoleukin okuqukethe ezinye izinto. Ngokombono wamakhemikhali, okwamanje akunakwenzeka ukuhlanganisa izinto ezinjalo ezisebenzayo.
Umuthi okuwukuphela kwawo osondelene ne-immunostimulant echaziwe ngokwesenzo sokwelashwa namuhla yi "Bioleukin", equkethe i-interleukin... Noma kunjalo, ngokusho kodokotela bezilwane abaningi, inketho yokuqala ekwelapheni izifo eziningi iyancomeka ngokubuka kokuphendula komzimba we-canine.
Kuzothakazelisa futhi:
- IPirantel yezinja
- Isichasiso sezinja
- UMaxidine wezinja
- Inqaba yezinja
Abafuyi bezinja abanokuhlangenwe nakho sekuyisikhathi eside baqaphela ukuthi izilwane ezifuywayo zanoma imuphi unyaka ziyakubekezelela ukuphathwa kwe-Roncoleukin kalula, futhi ngokunamathela ngokuqinile emithini yokwelashwa, izimpawu eziseceleni azikho nhlobo, futhi umphumela uyaqhubeka futhi uphakeme.
